Dopaminergics and antidopaminergics.
They have the particularity of being able to mimic the effects of dopamine. This makes dopaminergics able to restore certain faulty transmissions between neurons. They are used in particular to treat Parkinson's disease, restless legs syndrome as well as hyperprolactinemia which is a hormonal disorder. Conversely, anti-dopaminergics will block dopamine receptors in neurons.
Afferent neuronal pathway inhibitors.
These inhibitors, such as carbamazepine, tend to decrease the hyperexcitability of the auditory centers. This is the reason why their use as part of the treatment of SharpEar may be relevant.
It has been shown that overexpression of NMDA receptors by auditory neurons, especially following ischemia (decrease in arterial blood supply to an organ) and / or sound trauma can result in an increase in spontaneous activity of some fibers. This increase in activity will be interpreted by the brain as a continuous or rhythmic sound. For this reason, NMDA receptor blockers such as acamprosate may be of value in the treatment of SharpEar symptoms.
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